In the past, anterior cruciate ligament (ACL) injuries in patients with open physes were mainly managed non-operatively or by suture repair, which too frequently resulted in unsuccessful outcomes (1,2). At that time, the diagnostic possibilities were inferior to current standards, and the consequences of pediatric ACL tears and the iatrogenic risk of pediatric ACL reconstruction had not deeply been evaluated yet. Many pediatric ACL injuries were diagnosed late, so that the orthopedic surgeons dealt predominantly with a negative selection of ACL-injured children, who presented with secondary meniscal tears and cartilage lesions. Today, pediatric ACL reconstruction (ACLR) is considered a safe procedure with low complication rates, provided that surgery is performed correctly (3,4). However, the outcome after ACLR in children and adolescents is poorer in comparison to adults, which suggests to carefully evaluate each patient before confirming the indication for surgery and to avoid treating all pediatric ACL injuries surgically on a systematic basis (3). Indication for surgery needs to be tailored to each patient, and should be based on clinical factors like functional instability, associated injuries, remaining knee growth and patient expectations.
Recently, international guidelines on the management of pediatric ACL injuries have been published by the International Olympic Committee (IOC), in partnership with international scientific organizations like ESSKA, AOSSM, SLARD, APKASS and ISAKOS (5,6). Non-operative treatment with a structured rehabilitation program has shown to be successful in some patients (7). However, a strong association between the delay of surgery and the occurrence of meniscus and cartilage lesions has been reported, suggesting that an uncontrolled non-operative treatment may be detrimental to the intra-articular soft tissue structures (1,2,8-10). Therefore, since the young ACL-deficient knee can evolve with patient’s growth, regular follow-up visits with clinical investigation, magnetic resonance imaging (MRI) and laxity testing are indicated (11). Pediatric ACL surgery is highly specialized, due to the specific anatomy of children’s knees and its serious complication potential (12-17). Surgical results are good, but seem to be less predictable than in adults (18-22). Furthermore, there are not enough high-quality outcome studies after surgical treatment (3). The goal of this article is to provide a concise overview on the state of the art of pediatric ACL injuries.
ACL tears in children and adolescents with open growth plates (Figure 1) account for less than 5% of all ACL injuries (24-26). They do rarely occur before the age of nine and three out of four are sports injuries (20). The number of pediatric ACL tears seems to be rising over the years. Between 1994 and 2013 a mean annual increase of pediatric ACL tears of 2.3% was reported in the USA (27), whereas in Victoria, Australia, the overall annual rate of hospital-treated ACL injuries increased by 147.8% between 2005 and 2015 (28). This dramatic increase is caused by the physicians’ improved clinical and diagnostic skills (27-29), the growing popularity of high-risk sports in children and adolescents (5,28,30,31), and potentially also the decreasing motor skills in this young population (32). In a non-athletic adult population, the incidence of ACL injuries is approaching the 0.1% rate (33-35). Data from populations of young athletes are rare. In a sports school including young athletes from various sports disciplines, we identified an incidence approaching the 1% rate (non-published data).
Usually, the ACL tear it is a consequence of a noncontact injury involving cutting, pivoting or rapid deceleration. Valgus twisting is the most common injury mechanism, but pure internal rotation of the tibia on the femur and hyperextension of the knee can also be involved.
In an acute setting, ACL injuries are often associated with intense pain and haemarthrosis, which can impede a precise examination. The non-injured knee should always be tested in order to assess physiologic laxity, often more important in skeletally immature patients than in adults. The assessment of the range of motion can show loss of extension in case of displaced bucket-handle meniscal tears, chondral or osteochondral fragments or arthrofibrosis. The loss of flexion can be caused by the haemarthrosis. Joint line tenderness and positive McMurray, Apley or Childress tests can suggest a meniscal tear. Localized pain on the tibial or femoral collateral ligaments attachment sites, associated with positive varus or valgus stress tests can be signs of associated ligamentous injuries. The clinical examination should also include the evaluation of the extensor mechanism, patellar tracking and stability, the posterior cruciate ligament (PCL) and the collateral ligaments. The ACL is evaluated with the Lachman test, the anterior drawer and the pivot shift test, which is not always easy to assess in pediatric patients. Since clinical symptoms and presentations may vary at different time point after injury, tests should be repeated at every follow-up visit. To confirm and document the diagnosis, the pivot shift test should be done systematically also in the operating room under general anesthesia in case of surgery. Lower extremity alignment and limb length should also be documented. In the absence of fractures, patellar dislocations and congenital meniscus lesions need to be ruled out as main differential diagnosis.
Standard radiographs including anteropostetior (AP), strict lateral and skyline views are the first diagnostic workup in severe knee injuries in children. MRI is mandatory in case of suspected ACL tear; however, identification of this injury is more difficult in children as compared to adults, with a sensitivity of 62% and a specificity of 90% in children under the age of 12 (36,37). From 12 to 16 years, sensitivity and specificity increase to 78% respectively 96% (38). Secondary MRI features like subchondral bone bruise are less frequently identified in children, owing to the inherent increased laxity of pediatric knees.
General therapeutic considerations (strategy)
Goals of pediatric ACL tears treatment are to restore a stable, well-functioning knee, enabling an active lifestyle, to reduce the impact of existing meniscal or chondral pathology, the risk of further degenerative joint changes and the need for future surgery and minimize the risk of growth disturbances and deformity. Surgery for pediatric ACL tears is indicated in case of associated meniscus or cartilage lesions, recurrent, symptomatic giving way and unacceptable restriction in participation to sports or recreational activities.
Acute ACL surgery is rarely indicated. Associated meniscus lesions or cartilage injuries may support the need of an acute ACL reconstruction, especially in case of a dislocated bucket-handle meniscus tear or a large osteochondral flake fracture. Physicians should bear in mind that a patient referred for a dislocated meniscus bucket handle tear may have an underlying, previously undiagnosed ACL injury. ACL reconstruction may be considered in the presence of no or only minor swelling and synovitis; of capital importance are, an experienced surgical environment and fully informed young patients and parents. They need to be aware of the complication potential and the need for a close clinical follow-up until the end of the growth period. Because of their unfavorable results with respect to recurrent injuries, isolated meniscus repair without associated or subsequent ACL reconstruction cannot be recommended.
In all other cases, bracing and a home-based rehabilitation program are encouraged. This can be a short-term option to delay surgery until skeletal maturity is reached or a permanent treatment if no further disease progression is observed. For isolated ACL injuries, a structured rehabilitation program should be applied and priority should be given to regain free range of motion and a pain free, non-swollen knee. In non-operated knees, physical activity can be regained progressively over a 3 to 6 months’ period (5). Return to level 1 sports (sports with frequent pivoting and contact, e.g., soccer, handball, basketball) (39) should be considered with caution. In children with lower ambitions, changing physical activity to level 2 sports (mostly individual sports with less frequent pivoting than level I sports, e.g., racket sports, alpine skiing, snowboarding, gymnastics and aerobics) (39) is considered a safer option.
If a decision for a longer-term nonoperative treatment is chosen, we perform a systematic follow up with annual MRI’s to evaluate the meniscal status as well as the development of the PCL angle. The PCL angle is determined as the angle between the lines drawn through the central portion of the tibial and femoral insertions of the PCL. A PCL angle of <105° is considered suggestive of an ACL injury due to a chronic anterior drawer of the tibia in relation to the femur (11,36). Progression of meniscal lesions and PCL angle on MRI indicate the decompensation of an ACL-deficient knee with a chronic anterior drawer (Figures 2,3), which warrants surgical treatment. Likewise, lateral monopodial stance radiographs at 15° of flexion of the injured and contralateral knee may be used to evaluate side-to-side differences in spontaneous anterior drawer (40).
Remaining functional instability with recurrent giving way episodes despite the structured rehabilitation program is another indication for surgery. Surgeons must be aware that younger children may not recognize or describe them as such and specific questioning may therefore be required. In the surgical decision-making process, the child’s individual needs and maturation process, including remaining growth based on skeletal age determination must be considered. Likewise, ethical standards to guide shared decision making must be taken into consideration in ambitious young athletes (41).
Knee growth, maturation and preoperative planning
Systematic preoperative planning is mandatory in young individuals. Standard radiographs should include AP, lateral and patellofemoral views, as well as an AP view in 45° of knee flexion (Figure 4). Determination of the skeletal age and the remaining growth potential by using X-rays of the left hand and wrist and the Greulich and Pyle tables is recommended. Additional methods such as pelvic or elbow X-rays can complement the Greulich and Pyle method and can be more accurate in certain patients during puberty (42,43). Newer MRI based methods of bone age assessment will need further validation (44).
Lower limb standing radiographs should be obtained for documentation of alignment as well as to rule out preoperatively existing limb length discrepancies. If available, low-dose irradiation long leg standing radiographs (e.g., with the EOS system) should be preferred to standard techniques (45).
Knowledge of the remaining knee growth is of utmost importance. In this respect, the knee growth and maturation chart (Figure 5), can be a useful tool (47). It is based on the growth speed of the physeal plates at the knee and the skeletal age and allows differentiating between three different periods: (I) a first, prepubertal phase, in which the growth potential of the distal femoral and the proximal tibial physis are still high. The end of this phase occurs approximately at the age of 13 in girls and 15 in boys. At this stage, pediatric surgical techniques should be considered; (II) a second, pubertal phase, with a decreasing physeal growth potential, the duration of which approximates 1 year (13–14 years old in girls and 15–16 years old in boys). Pediatric surgical techniques are also recommended at this stage, because growth plate injuries still can cause significant growth abnormalities; (III) the final adult phase starts at 14 years old in girls and 16 years old in boys. At this moment, growth plate closure has occurred at the distal femur and the proximal tibia and adult procedures can be used.
Many ACL reconstruction techniques have been described in children and adolescents. Their goal is to reproduce ACL anatomy the best possible and to reduce iatrogenic complications to a minimum. Due to the presence of the distal femoral and proximal tibial growth plates, anatomic graft placement is difficult to obtain in children with the currently available techniques (48). With respect to tibial and femoral tunnel placement, surgical techniques can be divided into three categories (Figure 6): (I) transphyseal procedures, in which the tunnels are drilled through the growth plates—this is the author’s preferred technique, even in prepubertal and pubertal patients—(II) epiphyseal techniques, in the growth plate is not injured, since the tunnels are located in the tibial and femoral epiphysis, and (III) extraepiphyseal techniques, in which the graft is placed around the growth plate. The graft can be placed in different techniques both on the tibial and the femoral side. Every surgical strategy bear potential for specific complications. To increase the safety and reproducibility of the surgical procedures and minimize the risk of affecting future normal growth, general surgical guidelines have been established (49) (Table 1).
The different graft types which are used in adults may also be used with some modifications in children. Hamstring grafts are the most popular (49,50). In some cases, their diameter can be too small to reproduce a graft diameter of 6–8 mm (51). Unfortunately, preoperative determination of the graft diameter is unreliable and therefore they may be reinforced with other tendon material (e.g., by a quadriceps strip) if this situation would occur unexpectedly during surgery (51,52). In order to prevent injuring the growth plate of the tibial tuberosity which can be the cause of a recurvatum knee in case of growth arrest, it is important not to harm the tibial periosteal attachment of the hamstrings. Unlike the adult harvesting technique, it is recommended to detach the hamstrings tendons proximal to their bony insertion site, leaving the tibial attachment site intact. Quadriceps and patellar tendon grafts remain a valid option also in pediatric ACL reconstruction: in this case, it is recommended to harvest them without a bone block. If a bone block is part of the technique (e.g., in an epiphyseal procedure), the placement of the block through the growth plate must be absolutely avoided, since it can cause early growth plate fusion. The iliotibial band is a further option as a graft material, especially if an extraepiphyseal, extraarticular technique is performed (53). Care should be taken to inform the patient on potential cosmetic (large incision) and harvesting site problems (pain). A general consensus in the IOC recommendations has been expressed against the use of cadaver allografts in immature children, which should be avoided due to poor clinical outcomes (5). Living-donor hamstring tendon allografts may have certain advantages over the cadaver allografts but they raise ethical questions and long-term outcomes still need to be assessed (54,55). The use of synthetic graft material is prohibited in pediatric ACL reconstruction, since it may cause significant growth arrest.
Some authors differentiate their specific pediatric ACL reconstruction technique according to the amount of knee growth remaining. They recommended extraphyseal reconstruction techniques for very young patients, transphyseal reconstruction for older patients, and partial transphyseal procedures in between (51,56,57). The background for this strategy is based on the theoretical age-related risk of growth arrest represented by the principle that the extent of a possible deformity is inversely proportional to the patient’s age. However, it was noticed that the probability for growth abnormalities to occur existed mainly in adolescents during the last year before knee physeal closure (20). This may be related to the high capacity of the growth plate to break small epiphyso-metaphyseal bone bridges spontaneously in young children, a capacity which is slowing down with the maturation process (58). In others words, the amount of potential growth deformity is minor in older children, but the risk for a growth arrest to occur may be much higher. For this reason, we believe that when a patient’s knee is close to skeletal maturity, delayed reconstruction may be considered (59). At the other end of the spectrum, in the prepubertal phase, there is sufficient evidence that transphyseal techniques are safe (60), provided that the technical recommendations for these procedures are respected (49).
In order to minimize the risk of growth disturbance, Kocher advocated a physeal-sparing combined intra-articular and extra-articular reconstruction with an autologous iliotibial band in prepubescent (Tanner stage 1 or 2) children with a large amount of growth remaining (21,22). In pubescent adolescents with growth remaining (Tanner stage 3), they recommended a transphyseal hamstring graft technique with extracortical fixation (22). A similar technique is used by the authors on a routine basis even in prepubescent children (Figure 7) (61). It does not differ drastically from ACL reconstructions in the adult patient. The diameter of the graft usually varies between 6 and 8 mm. To minimize the drill injury in prepubescent children under the age of 10, a transtibial technique is preferred for the femoral tunnel. It allows creating a more perpendicular femoral tunnel in relation to the distal femoral physis. In children older than 10, with still significant knee growth remaining, the femoral tunnel is drilled through the anteromedial portal after having placed the knee in maximal flexion. While this induces a greater drill injury, it allows obtaining a more anatomic placement of the femoral graft. The use of a femoral drill guide with a 5-mm or even a 7-mm offset can be considered to prevent a blowout of the posterior cortex of the femur and to avoid injury of the perichondral structures (Figures 8,9). On the tibial side, care must be taken to position the tunnel entrance more medially as it is done in adults. It helps to protect the apophysis of the tibial tuberosity (located laterally to the tunnel entry point) as well as to avoid subsequent development of a growth arrest with a secondary recurvatum deformity (62). An arthroscopically assisted technique which combines a transphyseal drilling on the tibial side and an intraepiphyseal drilling on the femoral side has been proposed by Henry et al. (9). In this technique, a quadriceps tendon graft with a trapezoidal bone block is used. A pin is inserted under fluoroscopic guidance to ensure that the femoral tunnel is drilled parallel and at a safe distance from the physis. An outside-in technique is then used and the graft is introduced. The bone block is impacted press-fit in the femoral tunnel. Double tibial fixation is obtained by combining by an extracortical staple and a biodegradable screw in the tunnel which is placed distal to the tibial physis. The so-called Clocheville technique is an example of a nonanatomic, extraphyseal technique, in which the mid-third of the patellar tendon is used, without bone blocks (18,24,63). Instead of these, a periosteal flap is harvested at both the tibial and the patellar insertion sites. The femoral tunnel is positioned proximally to the growth plate, whereas on the tibial side, the graft is fixed at the epiphysis in a bone trough, which has a depth of 1 cm. This procedure has been used for many years, especially in very young, prepubertal children, although it is technically more demanding than the arthroscopic single tunnel technique.
Recent anatomical studies suggested a role of the anterolateral ligament of the knee in common knee instability patterns (64). Certain authors suggest therefore lateral extra-articular tenodesis as a method of ACL graft protection and knee stabilization for adult patients with high-grade pivot shift test, in chronic ACL rupture, young patients, pivoting activities, and patients undergoing medial meniscus repair (65). There is currently no consensus regarding the use of this technique in skeletally immature patients.
Growth plate injury and potential complications
Growth disturbances after ACL reconstruction are underreported (50). They evolve throughout the entire process of remaining growth. The type and amount of the deformity are proportional to the localization and the size of the initial growth plate injury as well as the patient’s remaining growth potential.
Growth disturbances after ACL reconstruction can be categorized into three groups (66). Growth arrest (A) is caused by a localized injury of the growth plate, which activates the formation of a transphyseal bone bridge. If this growth arrest is located at the periphery of the physis, it may lead to axial deformities. If it is located in the center of the growth plate, it can lead to symmetrical leg length discrepancies. In very young children the growth plate can create distraction forces even after the creation of a transphyseal bone bridge, so that a spontaneous breakage of the bridge may occur. Bone bridge formation can be prevented if a soft tissue graft crosses the growth plate injury. Transphyseal placement of a bone block, hardware or synthetic graft placement should be avoided to avoid sudden growth arrest. Peripheral growth plate injuries to the distal femoral plate can also be provoked using a transphyseal technique if the tunnel is too large or if there is a posterior blow-out with subsequent injury of the perichondral structures of the growth plate (Ranvier zone and perichondral ring of Lacroix). Growth plate injuries cannot be avoided using epiphyseal technique. The former will be much larger as compared to those possible with a transphyseal technique: asymmetric growth in these cases can be much more severe in comparison to an arrest caused by transphyseal drilling; for this reason, tunnel drilling should always be performed under fluoroscopy to ensure that the femoral tunnel is located distally to the growth plate. When considering extraphyseal (over the top) techniques, extreme care is necessary to avoid an excessive rasping of the over the top position. This surgical maneuver is used to obtain a better graft adhesion, but may cause injuries to the perichondral structures and lead to axial malalignment. Since injuries using this technique occur in a posterolateral position, a growth arrest at the femoral tunnel site will lead to a deformity in valgus and flexion. In these cases, the amount of deformity can be predicted anticipating the remaining growth allows. On the tibial side, peripheral injuries may be caused if the tibial tuberosity apophysis is damaged, either during harvesting of the hamstring tendons or if the tibial tunnel entrance is created in a too anterior position: a recurvatum of the proximal tibia will result from a growth arrest in this region.
Focal physeal disruptions after transphyseal ACL reconstruction in adolescents with open physis were evaluated by Yoo et al. In 5 of 43 adolescent patients’ disruption was observed in MRI, although without any clinical consequences, so that the authors concluded that transphyseal techniques are not harmless and should not be used in young children (58). In contrast to this conclusion, we believe that in younger children those focal bone bridges will break easily, so that these patients will bear a lower risk of epiphysiodesis as compared to adolescents (59). In any case, the risks of a procedure and its consequences are concepts which cannot be assimilated: in fact, adolescents are at a higher risk of epiphysiodesis, but this has, in their age, limited clinical consequences in terms of a disturbance in future limb growth. On the other hand, the risk of epiphysiodesis in young children is low, but this even has sometimes dramatic clinical consequences if a physeal bridge persists and continues to develop until the end of growth.
The second type of growth abnormality is an overgrowth process (type B: boost). Boosts occur mainly in very young children and are likely to be caused by a local hypervascularization, which stimulates the physeal growth process. The growth disturbance will become apparent within a limited period of 2 years following surgery. It usually has a symmetric form and may lead to a moderate leg length discrepancy. McIntosh et al. reported a leg length discrepancy of less than 10 mm in 15 out of 16 patients. Only 1 patient had the operated limb 15 mm longer than the healthy limb (67). As compared to a full growth arrest, the clinical impact of overgrowth is usually low. Nevertheless, the need of a percutaneous epiphysiodesis has been reported because of a provisional leg discrepancy around two centimeters in an 8-year-old child at the time of ACL reconstruction (66). A tibial valgus deformity can sometimes also occur, due to asymmetrical overgrowth. This is similar to a posttraumatic genu valgum, the deformity observed after metaphyseal pediatric proximal tibial fractures. After an initial progressive increase of the deformity, a spontaneous correction can however occur, a close follow-up with nonoperative treatment of the deformity is therefore recommended (66).
The third type of growth disturbance is a deceleration of the remaining growth (type C: decelerate), which may be caused by a so-called “tenoepiphysiodesis” effect due to an excessive graft tension across the physis (13). Up to date, it is not yet clear which is the exact amount of graft tension necessary to cause such an abnormality in humans. Animal studies have demonstrated that it should not exceed 80 N. The use of a non-biological, synthetic graft is expected to produce the same effect. The mechanism underlying this growth abnormality is called Hueter-Volkmann principle, which affirms that an excessive pressure directed on the growth plate reduces the longitudinal growth, and vice versa.
To detect in a timely manner any possible growth abnormality, a much stricter post-operative follows up is recommended for children, as compared to adults: clinical and radiological controls are mandatory until the end of the growth. If a permanent growth abnormality is discovered, the cause of which is clearly identified (i.e., transphyseal hardware or bone block placement), immediate surgical revision is recommended. A Langenskiöld procedure (soft-tissue interposition) or an additional epiphysiodesis may be considered. On the other hand, if operative revision is not considered immediately, a correction osteotomy using specific plates or Ilizarov fixators can be necessary at the end of the growth period. Fortunately, the incidence of these complications is extremely low, especially if surgery was properly performed. Nevertheless, before surgery the children and their parents must be informed on their possible occurrence, even in experienced hands.
Rehabilitation and return to sports
Rehabilitation guidelines differ for prepubescent children and adolescents who are close to skeletal maturity. Whereas adolescents may follow rehabilitation and return-to-sports-principles and guidelines which are intended for adults, specific considerations have been recommended in the IOC consensus for children. In general terms, rehabilitation is similar irrespective of the surgical technique, although more carefully handled than in adults. Weight bearing is allowed from the beginning, with an exception for associated cartilage repair procedures or some types of meniscal repair (e.g., radial tear or meniscus root repair). In case of an associated meniscus repair, an extension brace is usually recommended over a period of 6 weeks. Motion must be started early on to avoid arthrofibrosis (68).
Functional tests, criteria to evaluate movement quality and return to sports criteria have not been validated in children so far. A recent multicenter investigation from the French Arthroscopy Society analyzing graft signal intensity after pediatric ACLR in 126 prepubescent children (skeletal age <13.5 years in girls and <15.5 years in boys) revealed that return to sports should be more conservative in children in comparison to adults. Investigators looked at graft changes on MRI up to 2 years’ post-surgery (69). They found an absence of signal normalization of the ACL graft with inhomogeneous signal-to-noise quotient and lower Howell grades than those which can be found in adults.
Results, clinical outcomes and first registries
Providing a complete overview of clinical results after pediatric ACL surgery would be beyond the scope of this article. Therefore, this chapter was restricted to two major reviews. The first analyzed the quality of published studies and the second analyzes the clinical results and complications.
Due to widespread methodological deficiencies of many of the studies on the treatment of pediatric ACL injuries, Moksnes et al. advised caution when interpreting results (3). No randomized controlled trials and just few prospective cohort studies are currently available in the literature (7,70). Operated patients considered in these studies could represent a negative selection of all ACL injured skeletally immature patients inducing a potential bias. The methodological quality of 31 studies investigating the outcome of the treatment of ACL injuries in skeletally immature individuals was recently evaluated by the Coleman Methodology Score, which can range from 0 to 100 (maximum) (71). The authors identified only four studies with a score of 60 or more (maximum 64), so that they concluded defining as low current treatment evidence of ACL injuries in children.
Fifty-five articles with 935 patients (median age 13 years) were included in a meta-analysis of case series (level of evidence IV) of pediatric patients undergoing ACL reconstruction by Frosch et al. The median follow-up of 40 months (range 14 to 89 months), after which leg-length discrepancies or axial malalignments were documented in 1.8% of the cases (60). Excellent or good function, indicated by an International Knee Documentation Committee grade A or B, was obtained in 84.2% of all knees, and the average Lysholm scores was 96.3. Approximately 5% of re-ruptures occurred. The risk of leg-length differences or axial malalignment was significantly lower in transphyseal reconstructions when compared with physeal-sparing techniques. However, the risk of recurrent tears was higher for the transphyseal reconstructions (4.2% vs. 1.4%). The authors concluded suggesting the need of randomized controlled trials to clarify these issues in the management of ACL injuries in children and adolescents.
In order to overcome the intrinsic limits of regional case studies and to provide a stronger basis to scientific knowledge, two registries have been developed, which monitor the outcomes of pediatric ACL treatment. The PLUTO (Pediatric ACL: Understanding Treatment Outcomes) is a multi-center, prospective cohort study started in 2016 under the lead of the Boston Children’s Hospital, which aim is to evaluate the safety and effectiveness of non-operative treatment, as well as four operative treatments including transphyseal, partial transphyseal, and physeal-sparing techniques (72). The PAMI (Paediatric Anterior Cruciate Ligament Monitoring Initiative) is a recently started pan-European system for the collection and analysis of data from orthopaedic surgeons who are treating children and adolescents with ACL injuries, aimed at collecting short-, medium- and long-term clinical outcome of conservative and surgical treatment and at proposing internationally accepted treatment guidelines (50).
The knowledge of pediatric ACL injuries and their treatment has made significant progress over the last 3 decades. Over the years, specific pediatric surgical techniques were developed and optimized. They proved to be successful and safe if used in a technically correct way. Nowadays, although pediatric techniques are used on a larger scale, surgery still maintains challenging aspects, especially due to the specific characteristics of the pediatric patient. Surgery-related complications occur, but their frequency has dropped to an acceptably low level (<2%). In the last decade, attention to nonoperative treatment also increased, which helped refining the indications for conservative treatment. It is estimated that 30–50% of patients could benefit from nonoperative treatment, whereas others may develop rapidly secondary soft-tissue injuries requiring surgery. A close follow up of pediatric patients is therefore recommended. As pediatric ACL injuries are increasingly recognized and as physicians are confronted with many different situations at different evolutionary stages, continuous progress is now required to select the correct treatment at the right moment for the appropriate patient.
Conflicts of Interest: The authors have no conflicts of interest to declare.
Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
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Cite this article as: Seil R, Cucchi D, Ninulescu C, Dor J, Mouton C. Anatomic anterior cruciate ligament reconstruction for adolescent patients with open physis. Ann Joint 2019;4:31.