Society for translational medicine-expert consensus on the treatment of osteoarthritis

Dongquan Shi, Nicholas D. Clement, Rameah Bhonde, Shiro Ikegawa, Vasco V. Mascarenhas, Berardo Di Matteo, Pier Francesco Indelli, Nikolaos Kourkoumelis, E. Carlos Rodríguez-Merchán, Mohsen Sheykhhasan, Freddie H. Fu, Marco Aurélio Vaz, Jian Kong, Boris Gabin Kingue Azantsa, Chuan Ye, Farzin Halabchi, Stephen M. Cornish, Leslie R. M. Hausmann, André Luiz Siqueira Campos, Carlos César Lopes de Jesus, Christian Jorgensen, Elena M. Ilieva, Weiguo Wang, Laura Villarreal Martínez, Hyochol Ahn, Ivan V. Shirinsky, Corjena Cheung, Gunnar Knutsen, Wolf Petersen, Nancy E. Lane, Hong Cai, Wei Xu, Jian Wu, Jun Lu, Yingze Zhang, Qing Jiang

Abstract

Osteoarthritis (OA), also known as osteoarthrosis, is the most prevalent form of joint pathology. It is attributed to diverse causes like joint injury, obesity, aging, and genetic predisposition. The result is the degeneration of the articular cartilage, the subchondral bone, and the entire joint organ. The articular cartilage destruction, typical of OA, is associated with joint space narrowing and periarticular hypertrophic changes. Chronic knee pain significantly affects quality of life (1). People suffering from OA are often confused about the management of their condition. Healthcare professionals must provide support and clear advice on the possible ways to regulate symptoms like pain and decreased physical function, which have an impact on self-efficacy and social engagement.